Sell Quinine powder Cas 130-95-0

Sell Quinine powder Cas 130-95-0

Quinine is a medication used to treat malaria and babesiosis.^[4] This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available.^[4][5] While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects.^[4] It can be taken by mouth or intravenously.^[4] Malaria resistance to quinine occurs in certain areas of the world.^[4] Quinine is also used as an ingredient in tonic water to impart a bitter taste.^[6]

Common side effects include headache, ringing in the ears, vision issues, and sweating.^[4] More severe side effects include deafness, low blood platelets, and an irregular heartbeat.^[4] Use can make one more prone to sunburn.^[4] While it is unclear if use during pregnancy carries potential for fetal harm, treating malaria during pregnancy with quinine when appropriate is still recommended.^[4] Quinine is an alkaloid, a naturally occurring chemical compound.^[4] How it works as a medicine is not entirely clear.^[4]

Quinine was first isolated in 1820 from the bark of a cinchona tree, which is native to Peru,^[4][7][8] and its molecular formula was determined by Strecker in 1854.^[9] The class of chemical compounds to which it belongs is thus called the cinchona alkaloids. Bark extracts had been used to treat malaria since at least 1632 and it was introduced to Spain as early as 1636 by Jesuit missionaries returning from the New World.^[10] It is on the World Health Organization’s List of Essential Medicines.^[11][12] Treatment of malaria with quinine marks the first known use of a chemical compound to treat an infectious disease.

 

chinine; Cinchonan-9-ol, 6′-methoxy-, (8a,9R)-; (-)-Quinine; 6-Methoxycinchonine; 2-Quinuclidinemethanol, a-(6-methoxy-4-quinolyl)-5-vinyl-; Chinin; a-(6-Methoxy-4-quinolyl)-5-vinyl-2-quinuclidinemethanol; 6′-Methoxycinchonine; Cinchonan-9-ol, 6′-methoxy-, (8alpha,9R)-; (8S,9R)-Quinine; 6′-Methoxycinchonidine; (8S,9R)-6′-Methoxycinchonan-9-ol; NSC 192949;Quinine;Cinchonan-9-ol, 6-mnethoxy-; 6-Methoxycinchonan-9-ol; (8-a,9R)-6-Methoxycinchonan-9-ol; 6-Methoxycinchonine; a-(6-Methoxy-4-quinoyl)-5-vinyl-2-quinclidinemethanol (-)-Quinine

Key Spec Table

CAS #	EC Number	Hill Formula	Molar Mass
130-95-0	205-003-2	C₂₀H₂₄N₂O₂	324.42 g/mol

Pricing & Availability

Description
Catalogue Number	802304
Synonyms	6-Methoxy-a-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol, 6-Methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol

Product Information
CAS number	130-95-0
EC number	205-003-2
Hill Formula	C₂₀H₂₄N₂O₂
Molar Mass	324.42 g/mol
HS Code	2939 20 00
Structure formula Image
Quality Level	MQ200

Applications
Application	(-)-Quinine for resolution of racemates for synthesis. CAS 130-95-0, pH 9.0 (0.5 g/l, H₂O, 20 °C).

Physicochemical Information
Melting Point	173 – 175 °C (decomposition)
pH value	9.0 (0.5 g/l, H₂O, 20 °C)
Bulk density	110 – 140 kg/m3
Solubility	0.5 g/l

Safety Information according to GHS
Hazard Pictogram(s)
Hazard Statement(s)	H302: Harmful if swallowed. H317: May cause an allergic skin reaction.
Precautionary Statement(s)	P261: Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P264: Wash skin thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P280: Wear protective gloves. P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of water.
Signal Word	Warning
RTECS	VA6020000
Storage class	10 – 13 Other liquids and solids
WGK	WGK 1 slightly hazardous to water
Disposal	3 Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.

Safety Information
Categories of danger	sensitizing

Storage and Shipping Information
Storage	Store below +30°C.

Specifications
Assay (HClO₄)	≥ 99.0 %
Melting range (lower value)	≥ 174 °C
Melting range (upper value)	≤ 178 °C
Spec. rotation [α²0/D (c=1 in H₂SO₄ 0.1 mol/l)	-285.0 – -275.0 °
Identity (IR)	passes test

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